6VME

Human ESCRT-I heterotetramer headpiece

Summary for 6VME

• Entry DOI: 10.2210/pdb6vme/pdb
• Descriptor: Tumor susceptibility gene 101 protein, Vacuolar protein sorting-associated protein 37B, Multivesicular body subunit 12A, ... (5 entities in total)
• Functional Keywords: endosomal transport, hiv release, macroautophagy, protein transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 24
• Total formula weight: 204222.14

Authors

Flower, T.G.,Hurley, J.H.,Tjahjono, N. (deposition date: 2020-01-27, release date: 2020-05-20, Last modification date: 2023-10-11)

• Primary citation: Flower, T.G.,Takahashi, Y.,Hudait, A.,Rose, K.,Tjahjono, N.,Pak, A.J.,Yokom, A.L.,Liang, X.,Wang, H.G.,Bouamr, F.,Voth, G.A.,Hurley, J.H.; A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission.; Nat.Struct.Mol.Biol., 27:570-580, 2020; PubMed: 32424346; DOI: 10.1038/s41594-020-0426-4

Experimental method

X-RAY DIFFRACTION (2.19 Å)