6VMC

T4H2 T cell receptor bound to HLA-A2 presenting gp100T2L peptide (ILDQVPFSV)

Summary for 6VMC

• Entry DOI: 10.2210/pdb6vmc/pdb
• Descriptor: T4H2 T cell receptor alpha chain, T4H2 T cell receptor beta chain, MHC class I antigen, A-2 alpha chain, ... (7 entities in total)
• Functional Keywords: tcr, mhc class i, hla a2, melanoma, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 95039.29

Authors

Smith, A.R.,Baker, B.M. (deposition date: 2020-01-27, release date: 2021-01-20, Last modification date: 2024-10-30)

• Primary citation: Smith, A.R.,Alonso, J.A.,Ayres, C.M.,Singh, N.K.,Hellman, L.M.,Baker, B.M.; Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner; Proc.Natl.Acad.Sci.USA, 118:e2018125118-, 2021; DOI: 10.1073/pnas.2018125118

Experimental method

X-RAY DIFFRACTION (2.85 Å)