6VM9
T4H2 T cell receptor bound to HLA-A2 presenting gp100T2M peptide (IMDQVPFSV)
Summary for 6VM9
Entry DOI | 10.2210/pdb6vm9/pdb |
Descriptor | MHC class I antigen, A-2 alpha chain, Beta-2-microglobulin, Melanocyte protein PMEL, ... (5 entities in total) |
Functional Keywords | tcr, mhc class i, hla a2, melanoma, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 94965.24 |
Authors | Smith, A.R.,Baker, B.M. (deposition date: 2020-01-27, release date: 2021-01-20, Last modification date: 2023-10-11) |
Primary citation | Smith, A.R.,Alonso, J.A.,Ayres, C.M.,Singh, N.K.,Hellman, L.M.,Baker, B.M. Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner Proc.Natl.Acad.Sci.USA, 118:e2018125118-, 2021 Cited by DOI: 10.1073/pnas.2018125118PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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