6VLR

BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab

Summary for 6VLR

• Entry DOI: 10.2210/pdb6vlr/pdb
• EMDB information: 21232
• Descriptor: Envelope glycoprotein gp120, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: hiv, antibody, fab, vaccine, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 14
• Total formula weight: 334874.94

Authors

Cottrell, C.A.,Ward, A.B. (deposition date: 2020-01-24, release date: 2020-06-24, Last modification date: 2020-09-16)

• Primary citation: Cottrell, C.A.,van Schooten, J.,Bowman, C.A.,Yuan, M.,Oyen, D.,Shin, M.,Morpurgo, R.,van der Woude, P.,van Breemen, M.,Torres, J.L.,Patel, R.,Gross, J.,Sewall, L.M.,Copps, J.,Ozorowski, G.,Nogal, B.,Sok, D.,Rakasz, E.G.,Labranche, C.,Vigdorovich, V.,Christley, S.,Carnathan, D.G.,Sather, D.N.,Montefiori, D.,Silvestri, G.,Burton, D.R.,Moore, J.P.,Wilson, I.A.,Sanders, R.W.,Ward, A.B.,van Gils, M.J.; Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.; Plos Pathog., 16:e1008753-e1008753, 2020; PubMed: 32866207; DOI: 10.1371/journal.ppat.1008753

Experimental method