6VLD
Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP
Summary for 6VLD
Entry DOI | 10.2210/pdb6vld/pdb |
Descriptor | Alpha-(1,6)-fucosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARAGINE, ... (6 entities in total) |
Functional Keywords | fut8, fucosyltransferase, glycosyltransferase, n-glycan, core fucose, sh3 domain, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 230828.36 |
Authors | Jarva, M.A.,Dramicanin, M.,Lingford, J.P.,Mao, R.,John, A.,Goddard-Borger, E.D. (deposition date: 2020-01-23, release date: 2020-02-26, Last modification date: 2023-10-11) |
Primary citation | Jarva, M.A.,Dramicanin, M.,Lingford, J.P.,Mao, R.,John, A.,Jarman, K.E.,Grinter, R.,Goddard-Borger, E.D. Structural basis of substrate recognition and catalysis by fucosyltransferase 8. J.Biol.Chem., 295:6677-6688, 2020 Cited by PubMed: 32220931DOI: 10.1074/jbc.RA120.013291 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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