6VLD

Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP

6VLD の概要

• エントリーDOI: 10.2210/pdb6vld/pdb
• 分子名称: Alpha-(1,6)-fucosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARAGINE, ... (6 entities in total)
• 機能のキーワード: fut8, fucosyltransferase, glycosyltransferase, n-glycan, core fucose, sh3 domain, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 230828.36

構造登録者

Jarva, M.A.,Dramicanin, M.,Lingford, J.P.,Mao, R.,John, A.,Goddard-Borger, E.D. (登録日: 2020-01-23, 公開日: 2020-02-26, 最終更新日: 2023-10-11)

• 主引用文献: Jarva, M.A.,Dramicanin, M.,Lingford, J.P.,Mao, R.,John, A.,Jarman, K.E.,Grinter, R.,Goddard-Borger, E.D.; Structural basis of substrate recognition and catalysis by fucosyltransferase 8.; J.Biol.Chem., 295:6677-6688, 2020; PubMed: 32220931; DOI: 10.1074/jbc.RA120.013291

実験手法

X-RAY DIFFRACTION (2.28 Å)