6VL9

Anti-PEG antibody 6-3 Fab fragment in complex with PEG

Summary for 6VL9

Entry DOI	10.2210/pdb6vl9/pdb
Descriptor	6-3 Fab heavy chain, 6-3 Fab light chain, 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, ... (4 entities in total)
Functional Keywords	antibody, fab, peg, anti-peg, polymer, anti-drug, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	98506.38
Authors	Nicely, N.I.,Huckaby, J.T.,Lai, S.K.,Jacobs, T.M. (deposition date: 2020-01-23, release date: 2020-09-09, Last modification date: 2024-10-30)
Primary citation	Huckaby, J.T.,Jacobs, T.M.,Li, Z.,Perna, R.J.,Wang, A.,Nicely, N.I.,Lai, S.K. Structure of an anti-PEG antibody reveals an open ring that captures highly flexible PEG polymers Commun Chem, 3:124-, 2020 Cited by DOI: 10.1038/s42004-020-00369-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.63 Å)

Structure validation