6VL8

Anti-PEG antibody 6-3 Fab fragment in complex with PEG

Summary for 6VL8

• Entry DOI: 10.2210/pdb6vl8/pdb
• Descriptor: 6-3 Fab heavy chain, 6-3 Fab light chain, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: antibody, fab, peg, anti-peg, polymer, anti-drug, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 8
• Total formula weight: 197843.76

Authors

Nicely, N.I.,Huckaby, J.T.,Lai, S.K.,Jacobs, T.M. (deposition date: 2020-01-23, release date: 2020-09-09, Last modification date: 2023-10-11)

• Primary citation: Huckaby, J.T.,Jacobs, T.M.,Li, Z.,Perna, R.J.,Wang, A.,Nicely, N.I.,Lai, S.K.; Structure of an anti-PEG antibody reveals an open ring that captures highly flexible PEG polymers; Commun Chem, 3:124-, 2020; DOI: 10.1038/s42004-020-00369-y

Experimental method

X-RAY DIFFRACTION (2.42 Å)