6VJB

Crystal structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes

6VJB の概要

• エントリーDOI: 10.2210/pdb6vjb/pdb
• 分子名称: Putative cell envelope proteinase, 1,2-ETHANEDIOL, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: vaccine, serine-protease, group a streptococcus, immune system
• 由来する生物種: Streptococcus pyogenes
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 175602.04

構造登録者

Malito, E.,Rouse, S. (登録日: 2020-01-15, 公開日: 2020-04-15, 最終更新日: 2023-10-11)

• 主引用文献: McKenna, S.,Malito, E.,Rouse, S.L.,Abate, F.,Bensi, G.,Chiarot, E.,Micoli, F.,Mancini, F.,Gomes Moriel, D.,Grandi, G.,Mossakowska, D.,Pearson, M.,Xu, Y.,Pease, J.,Sriskandan, S.,Margarit, I.,Bottomley, M.J.,Matthews, S.; Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes.; Comput Struct Biotechnol J, 18:650-660, 2020; PubMed: 32257048; DOI: 10.1016/j.csbj.2020.03.004

実験手法

X-RAY DIFFRACTION (2.24 Å)