6VIE
Structure of caspase-1 in complex with gasdermin D
Summary for 6VIE
Entry DOI | 10.2210/pdb6vie/pdb |
Descriptor | Caspase-1 subunit p20, Caspase-1 subunit p10, Gasdermin-D (3 entities in total) |
Functional Keywords | dual site recognition, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 133602.20 |
Authors | Liu, Z.,Xiao, T.S. (deposition date: 2020-01-13, release date: 2020-07-01, Last modification date: 2023-10-11) |
Primary citation | Liu, Z.,Wang, C.,Yang, J.,Chen, Y.,Zhou, B.,Abbott, D.W.,Xiao, T.S. Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage. Immunity, 53:106-, 2020 Cited by PubMed: 32553275DOI: 10.1016/j.immuni.2020.06.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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