6VGR
Crystal Structure of Human Dipeptidase 3 in Complex with Fab of SC-003
Summary for 6VGR
Entry DOI | 10.2210/pdb6vgr/pdb |
Descriptor | Dipeptidase 3, SC-003 Fab Heavy Chain, SC-003 Fab Light Chain, ... (4 entities in total) |
Functional Keywords | fab, antibody drug conjugate, dipeptidase, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 203286.86 |
Authors | Hayashi, K.,Longenecker, K.L.,Vivona, S. (deposition date: 2020-01-08, release date: 2020-05-13, Last modification date: 2023-10-11) |
Primary citation | Hayashi, K.,Longenecker, K.L.,Koenig, P.,Prashar, A.,Hampl, J.,Stoll, V.,Vivona, S. Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity. J.Struct.Biol., 211:107512-107512, 2020 Cited by PubMed: 32325220DOI: 10.1016/j.jsb.2020.107512 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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