6VE5

X-ray structure of human REV7 in complex with Shieldin3 (residues 41-74)

6VE5 の概要

• エントリーDOI: 10.2210/pdb6ve5/pdb
• 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: dna damage response, dna double-strand break repair, dna end resection, homologous recombination, non-homologous end joining, shieldin3, shld3, rinn1, rev7, 53bp1, rif1, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28986.59

構造登録者

Cui, G.,Botuyan, M.V.,Mer, G. (登録日: 2019-12-28, 公開日: 2021-01-13, 最終更新日: 2023-10-11)

• 主引用文献: Du Truong, C.,Craig, T.A.,Cui, G.,Botuyan, M.V.,Serkasevich, R.A.,Chan, K.Y.,Mer, G.,Chiu, P.L.,Kumar, R.; Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta.; J.Biol.Chem., 297:100912-100912, 2021; PubMed: 34174285; DOI: 10.1016/j.jbc.2021.100912

実験手法

X-RAY DIFFRACTION (2 Å)