6V9T

Tudor domain of TDRD3 in complex with a small molecule

This is a non-PDB format compatible entry.

Summary for 6V9T

• Entry DOI: 10.2210/pdb6v9t/pdb
• Descriptor: Tudor domain-containing protein 3, 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 18590.94

Authors

Li, W.,Tempel, W.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2019-12-16, release date: 2019-12-25, Last modification date: 2023-10-18)

• Primary citation: Liu, Y.,Iqbal, A.,Li, W.,Ni, Z.,Wang, Y.,Ramprasad, J.,Abraham, K.J.,Zhang, M.,Zhao, D.Y.,Qin, S.,Loppnau, P.,Jiang, H.,Guo, X.,Brown, P.J.,Zhen, X.,Xu, G.,Mekhail, K.,Ji, X.,Bedford, M.T.,Greenblatt, J.F.,Min, J.; A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.; Nat Commun, 13:5453-5453, 2022; PubMed: 36114190; DOI: 10.1038/s41467-022-33229-5

Experimental method

X-RAY DIFFRACTION (2.154 Å)