6V7N
Crystal Structure of a human Lysosome Resident Glycoprotein, Lysosomal Acid Lipase, and its Implications in Cholesteryl Ester Storage Disease (CESD)
Summary for 6V7N
Entry DOI | 10.2210/pdb6v7n/pdb |
Descriptor | Lysosomal acid lipase/cholesteryl ester hydrolase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | lysosomal acid lipase, cholesteryl ester storage disease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 89239.68 |
Authors | |
Primary citation | Rajamohan, F.,Reyes, A.R.,Tu, M.,Nedoma, N.L.,Hoth, L.R.,Schwaid, A.G.,Kurumbail, R.G.,Ward, J.,Han, S. Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage disease. J.Lipid Res., 61:1192-1202, 2020 Cited by PubMed: 32482718DOI: 10.1194/jlr.RA120000748 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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