6V6Y

Crystal Structure of T. thermophilus methylenetetrahydrofolate dehydrogenase (MTHFD)

6V6Y の概要

• エントリーDOI: 10.2210/pdb6v6y/pdb
• 分子名称: Bifunctional protein FolD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• 機能のキーワード: amino-acid biosynthesis, histidine biosynthesis, hydrolase, methionine biosynthesis, multifunctional enzyme, nadp, one-carbon metabolism, oxidoreductase, purine biosynthesis
• 由来する生物種: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30984.54

構造登録者

Maiello, F.,Coelho, C.,Gallo, G.,Sucharski, F.,Hardy, L.,Wurtele, M. (登録日: 2019-12-06, 公開日: 2020-05-27, 最終更新日: 2023-10-11)

• 主引用文献: Maiello, F.,Gallo, G.,Coelho, C.,Sucharski, F.,Hardy, L.,Wurtele, M.; Crystal structure of Thermus thermophilus methylenetetrahydrofolate dehydrogenase and determinants of thermostability.; Plos One, 15:e0232959-e0232959, 2020; PubMed: 32401802; DOI: 10.1371/journal.pone.0232959

実験手法

X-RAY DIFFRACTION (2.15201566872 Å)