6V62

SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine

6V62 の概要

• エントリーDOI: 10.2210/pdb6v62/pdb
• 分子名称: Actin, cytoplasmic 1, Actin-histidine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• 機能のキーワード: transferase, transferase-structural protein complex, transferase/structural protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70958.15

構造登録者

Dai, S.,Horton, J.R.,Cheng, X. (登録日: 2019-12-04, 公開日: 2020-01-15, 最終更新日: 2023-10-11)

• 主引用文献: Dai, S.,Horton, J.R.,Wilkinson, A.W.,Gozani, O.,Zhang, X.,Cheng, X.; An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.; J.Biol.Chem., 295:2582-2589, 2020; PubMed: 31911441; DOI: 10.1074/jbc.RA119.012319

実験手法

X-RAY DIFFRACTION (2.36 Å)