6V3X

Crystal structure of EED in complex with PALI1-K1241me3 peptide

Summary for 6V3X

• Entry DOI: 10.2210/pdb6v3x/pdb
• Descriptor: Polycomb protein EED, PALI1 peptide (3 entities in total)
• Functional Keywords: eed, pali1, lcor, c10orf12, tri-methyl-lysine, gene regulation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 43089.20

Authors

Zhang, Q.,Davidovich, C. (deposition date: 2019-11-26, release date: 2021-05-26, Last modification date: 2023-10-11)

• Primary citation: Zhang, Q.,Agius, S.C.,Flanigan, S.F.,Uckelmann, M.,Levina, V.,Owen, B.M.,Davidovich, C.; PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.; Nat Commun, 12:4592-4592, 2021; PubMed: 34321472; DOI: 10.1038/s41467-021-24866-3

Experimental method

X-RAY DIFFRACTION (1.7 Å)