6V08
Crystal structure of human recombinant Beta-2 glycoprotein I (hrB2GPI)
6V08 の概要
エントリーDOI | 10.2210/pdb6v08/pdb |
関連するPDBエントリー | 1C1Z |
分子名称 | Beta-2-glycoprotein 1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
機能のキーワード | plasma glycoprotein, coagulation, innate immune system, autoimmunity, thrombosis, sushi domain, blood clotting |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 41746.27 |
構造登録者 | Chen, Z.,Ruben, E.A.,Planer, W.,Chinnaraj, M.,Zuo, X.,Pengo, V.,Macor, P.,Tedesco, F.,Pozzi, N. (登録日: 2019-11-18, 公開日: 2020-06-17, 最終更新日: 2023-10-11) |
主引用文献 | Ruben, E.,Planer, W.,Chinnaraj, M.,Chen, Z.,Zuo, X.,Pengo, V.,De Filippis, V.,Alluri, R.K.,McCrae, K.R.,Macor, P.,Tedesco, F.,Pozzi, N. The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome. J.Biol.Chem., 295:10794-10806, 2020 Cited by PubMed: 32518155DOI: 10.1074/jbc.RA120.013939 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.58 Å) |
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