6UYH

Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP

Summary for 6UYH

• Entry DOI: 10.2210/pdb6uyh/pdb
• Related: 6NAB
• Descriptor: Prolyl-tRNA synthetase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... (7 entities in total)
• Functional Keywords: ssgcid, structural genomics, halofuginone, amppnp, seattle structural genomics center for infectious disease, ligase
• Biological source: Naegleria fowleri (Brain eating amoeba)
• Total number of polymer chains: 2
• Total formula weight: 122461.07

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-11-13, release date: 2019-11-27, Last modification date: 2023-10-11)

• Primary citation: Dranow, D.M.,Abendroth, J.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.75 Å)