6UYH

Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP

6UYH の概要

• エントリーDOI: 10.2210/pdb6uyh/pdb
• 関連するPDBエントリー: 6NAB
• 分子名称: Prolyl-tRNA synthetase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... (7 entities in total)
• 機能のキーワード: ssgcid, structural genomics, halofuginone, amppnp, seattle structural genomics center for infectious disease, ligase
• 由来する生物種: Naegleria fowleri (Brain eating amoeba)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 122461.07

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2019-11-13, 公開日: 2019-11-27, 最終更新日: 2023-10-11)

• 主引用文献: Dranow, D.M.,Abendroth, J.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (1.75 Å)