6UUW
Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA
Summary for 6UUW
Entry DOI | 10.2210/pdb6uuw/pdb |
EMDB information | 20902 |
Descriptor | ATP-citrate synthase, ADENOSINE-5'-DIPHOSPHATE, COENZYME A, ... (6 entities in total) |
Functional Keywords | lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 489799.92 |
Authors | Wei, X.,Marmorstein, R. (deposition date: 2019-11-01, release date: 2019-12-25, Last modification date: 2024-05-29) |
Primary citation | Wei, X.,Schultz, K.,Bazilevsky, G.A.,Vogt, A.,Marmorstein, R. Molecular basis for acetyl-CoA production by ATP-citrate lyase Nat.Struct.Mol.Biol., 27:33-41, 2020 Cited by PubMed: 31873304DOI: 10.1038/s41594-019-0351-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.85 Å) |
Structure validation
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