6URX
Crystal structure of ricin A chain in complex with inhibitor 5-phenyl-2-thiophenecarboxylic acid
Summary for 6URX
Entry DOI | 10.2210/pdb6urx/pdb |
Descriptor | Ricin, 1,2-ETHANEDIOL, 5-phenylthiophene-2-carboxylic acid, ... (5 entities in total) |
Functional Keywords | ricin a chain, rta, hydrolase, toxin, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Ricinus communis (Castor bean) |
Total number of polymer chains | 1 |
Total formula weight | 31281.35 |
Authors | Harijan, R.K.,Li, X.P.,Bonanno, J.B.,Almo, S.C.,Tumer, N.E.,Schramm, V.L. (deposition date: 2019-10-24, release date: 2020-06-17, Last modification date: 2023-10-11) |
Primary citation | Li, X.P.,Harijan, R.K.,Kahn, J.N.,Schramm, V.L.,Tumer, N.E. Small Molecule Inhibitors Targeting the Interaction of Ricin Toxin A Subunit with Ribosomes. Acs Infect Dis., 6:1894-1905, 2020 Cited by PubMed: 32428396DOI: 10.1021/acsinfecdis.0c00127 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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