6URM

Crystal structure of vaccine-elicited receptor-binding site targeting antibody LPAF-a.01 in complex with Hemagglutinin H1 A/California/04/2009

6URM の概要

• エントリーDOI: 10.2210/pdb6urm/pdb
• 分子名称: Hemagglutinin, The heavy chain of antibody LPAF-a.01, The light chain of antibody LPAF-a.01, ... (9 entities in total)
• 機能のキーワード: influenza, antibody, receptor-binding site, immune system, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 209012.82

構造登録者

Zhou, T.,Cheung, S.F.,Kwong, P.D. (登録日: 2019-10-23, 公開日: 2020-09-16, 最終更新日: 2023-10-11)

• 主引用文献: Cheung, C.S.,Fruehwirth, A.,Paparoditis, P.C.G.,Shen, C.H.,Foglierini, M.,Joyce, M.G.,Leung, K.,Piccoli, L.,Rawi, R.,Silacci-Fregni, C.,Tsybovsky, Y.,Verardi, R.,Wang, L.,Wang, S.,Yang, E.S.,Zhang, B.,Zhang, Y.,Chuang, G.Y.,Corti, D.,Mascola, J.R.,Shapiro, L.,Kwong, P.D.,Lanzavecchia, A.,Zhou, T.; Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation.; Cell Rep, 32:108088-108088, 2020; PubMed: 32877670; DOI: 10.1016/j.celrep.2020.108088

実験手法

X-RAY DIFFRACTION (2.65 Å)