6URF
Malic enzyme from Mycobacterium tuberculosis
Summary for 6URF
Entry DOI | 10.2210/pdb6urf/pdb |
Descriptor | NAD-dependent malic enzyme, GLYCEROL (3 entities in total) |
Functional Keywords | malic enzyme, fatty acid synthesis, glucose metabolism, cytosolic protein, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 4 |
Total formula weight | 248624.78 |
Authors | Cuthbert, B.J.,Burley, K.H.,Goulding, C.W.,Mathews, E.I.,Beste, D.J. (deposition date: 2019-10-23, release date: 2020-10-28, Last modification date: 2023-10-11) |
Primary citation | Burley, K.H.,Cuthbert, B.J.,Basu, P.,Newcombe, J.,Irimpan, E.M.,Quechol, R.,Foik, I.P.,Mobley, D.L.,Beste, D.J.V.,Goulding, C.W. Structural and Molecular Dynamics of Mycobacterium tuberculosis Malic Enzyme, a Potential Anti-TB Drug Target. Acs Infect Dis., 7:174-188, 2021 Cited by PubMed: 33356117DOI: 10.1021/acsinfecdis.0c00735 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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