6UQV

Crystal structure of ChoE, a bacterial acetylcholinesterase from Pseudomonas aeruginosa

Summary for 6UQV

• Entry DOI: 10.2210/pdb6uqv/pdb
• Descriptor: ChoE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... (7 entities in total)
• Functional Keywords: esterase, acetylcholine, prokaryotic, acetylcholinesterase, hydrolase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 1
• Total formula weight: 32236.51

Authors

Shi, R.,Pham, V.D.,To, T.A. (deposition date: 2019-10-21, release date: 2020-05-13, Last modification date: 2020-07-08)

• Primary citation: Pham, V.D.,To, T.A.,Gagne-Thivierge, C.,Couture, M.,Lague, P.,Yao, D.,Picard, M.E.,Lortie, L.A.,Attere, S.A.,Zhu, X.,Levesque, R.C.,Charette, S.J.,Shi, R.; Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism.; J.Biol.Chem., 295:8708-8724, 2020; PubMed: 32371400; DOI: 10.1074/jbc.RA119.011809

Experimental method

X-RAY DIFFRACTION (1.35 Å)