6UPG
Crystal structure of Mycobacterium tuberculosis CYP121 in complex with cYF-4-OMe
Summary for 6UPG
Entry DOI | 10.2210/pdb6upg/pdb |
Descriptor | Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, (3~{S},6~{S})-3-[(4-hydroxyphenyl)methyl]-6-[(4-methoxyphenyl)methyl]piperazine-2,5-dione, ... (4 entities in total) |
Functional Keywords | analog, c-c, unusual, p450, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 44131.53 |
Authors | Nguyen, R.C.D.,Yang, Y.,Liu, A. (deposition date: 2019-10-17, release date: 2020-04-29, Last modification date: 2023-10-11) |
Primary citation | Nguyen, R.C.,Yang, Y.,Davis, I.,Liu, A. Substrate-Assisted Hydroxylation and O-Demethylation in the Peroxidase-like Cytochrome P450 Enzyme CYP121 Acs Catalysis, 10:1628-1639, 2020 Cited by DOI: 10.1021/acscatal.9b04596PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.393 Å) |
Structure validation
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