6UPG

Crystal structure of Mycobacterium tuberculosis CYP121 in complex with cYF-4-OMe

6UPG の概要

• エントリーDOI: 10.2210/pdb6upg/pdb
• 分子名称: Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, (3~{S},6~{S})-3-[(4-hydroxyphenyl)methyl]-6-[(4-methoxyphenyl)methyl]piperazine-2,5-dione, ... (4 entities in total)
• 機能のキーワード: analog, c-c, unusual, p450, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44131.53

構造登録者

Nguyen, R.C.D.,Yang, Y.,Liu, A. (登録日: 2019-10-17, 公開日: 2020-04-29, 最終更新日: 2023-10-11)

• 主引用文献: Nguyen, R.C.,Yang, Y.,Davis, I.,Liu, A.; Substrate-Assisted Hydroxylation and O-Demethylation in the Peroxidase-like Cytochrome P450 Enzyme CYP121; Acs Catalysis, 10:1628-1639, 2020; DOI: 10.1021/acscatal.9b04596

実験手法

X-RAY DIFFRACTION (1.393 Å)