6UNR

Kinase domain of ALK2-K492A/K493A with AMPPNP

Summary for 6UNR

• Entry DOI: 10.2210/pdb6unr/pdb
• Related: 6UNQ
• Descriptor: Activin receptor type-1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: kinase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 38759.97

Authors

Agnew, C.,Jura, N. (deposition date: 2019-10-13, release date: 2021-07-07, Last modification date: 2023-10-11)

• Primary citation: Agnew, C.,Ayaz, P.,Kashima, R.,Loving, H.S.,Ghatpande, P.,Kung, J.E.,Underbakke, E.S.,Shan, Y.,Shaw, D.E.,Hata, A.,Jura, N.; Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization.; Nat Commun, 12:4950-4950, 2021; PubMed: 34400635; DOI: 10.1038/s41467-021-25248-5

Experimental method

X-RAY DIFFRACTION (2.2 Å)