6UNB
Crystal structure of CTX-M-14 in complex with temocillin
Summary for 6UNB
Entry DOI | 10.2210/pdb6unb/pdb |
Related | 6UN1 6UN3 |
Descriptor | Beta-lactamase, (2R,4S)-2-[(1S)-1-{[(2R)-2-carboxy-2-(thiophen-3-yl)acetyl]amino}-1-methoxy-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4 -carboxylic acid, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | temocillin, ticarcillin, b-lactam, lactam, penicillin, ctx-m-14 beta-lactamase, esbl, extended spectrum b-lactamase, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 57179.85 |
Authors | |
Primary citation | Sacco, M.D.,Kroeck, K.G.,Kemp, M.T.,Zhang, X.,Andrews, L.D.,Chen, Y. Influence of the alpha-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 beta-Lactamase. Antimicrob.Agents Chemother., 64:-, 2019 Cited by PubMed: 31685462DOI: 10.1128/AAC.01473-19 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
Download full validation report