6UN3

Crystal structure of Pseudomonas aeruginosa PBP3 in complex with ticarcillin

Summary for 6UN3

• Entry DOI: 10.2210/pdb6un3/pdb
• Related: 6UN1 6UNB
• Descriptor: Peptidoglycan D,D-transpeptidase FtsI, GLYCEROL, (2R,4S)-2-[(1R)-1-{[(2R)-2-carboxy-2-(thiophen-3-yl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (5 entities in total)
• Functional Keywords: temocillin, ticarcillin, pseudomonas aeruginosa pbp3, penicillin-binding protein 3, transpeptidase, hmm, high-molecular mass, b-lactam, lactam, penicillin, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 1
• Total formula weight: 58157.33

Authors

Sacco, M.,Chen, Y. (deposition date: 2019-10-10, release date: 2019-10-30, Last modification date: 2023-10-11)

• Primary citation: Sacco, M.D.,Kroeck, K.G.,Kemp, M.T.,Zhang, X.,Andrews, L.D.,Chen, Y.; Influence of the alpha-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 beta-Lactamase.; Antimicrob.Agents Chemother., 64:-, 2019; PubMed: 31685462; DOI: 10.1128/AAC.01473-19

Experimental method

X-RAY DIFFRACTION (1.9 Å)