6UMJ

Crystal structure of erenumab Fab-c

Summary for 6UMJ

• Entry DOI: 10.2210/pdb6umj/pdb
• Related: 6UMG 6UMH 6UMI
• Descriptor: erenumab Fab heavy chain, IgG1, erenumab Fab light chain, IgG1, 1,3-BUTANEDIOL, ... (5 entities in total)
• Functional Keywords: fragment antigen binding, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 48637.32

Authors

Mohr, C. (deposition date: 2019-10-09, release date: 2020-02-12, Last modification date: 2020-02-26)

• Primary citation: Garces, F.,Mohr, C.,Zhang, L.,Huang, C.S.,Chen, Q.,King, C.,Xu, C.,Wang, Z.; Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab).; Cell Rep, 30:1714-, 2020; PubMed: 32049005; DOI: 10.1016/j.celrep.2020.01.029

Experimental method

X-RAY DIFFRACTION (2.7 Å)