6UM2

Structure of M-6-P/IGFII Receptor and IGFII complex

Summary for 6UM2

• Entry DOI: 10.2210/pdb6um2/pdb
• EMDB information: 20816
• Descriptor: Cation-independent mannose-6-phosphate receptor, Insulin-like growth factor II, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: m-6-p, igfii, receptor, sugar binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 283994.25

Authors

Wang, R.,Qi, X.,Li, X. (deposition date: 2019-10-08, release date: 2020-02-26, Last modification date: 2020-07-29)

• Primary citation: Wang, R.,Qi, X.,Schmiege, P.,Coutavas, E.,Li, X.; Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments; Sci Adv, 6:eaaz1466-, 2020; DOI: 10.1126/sciadv.aaz1466

Experimental method

ELECTRON MICROSCOPY (4.32 Å)