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6UL9

Crystal structure of human GAC in complex with inhibitor UPGL00023

Summary for 6UL9
Entry DOI10.2210/pdb6ul9/pdb
DescriptorGlutaminase kidney isoform, mitochondrial, 2-phenyl-N-{5-[(1-{5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}azetidin-3-yl)oxy]-1,3,4-thiadiazol-2-yl}acetamide (3 entities in total)
Functional Keywordsinhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight233223.35
Authors
Huang, Q.Q.,Cerione, R.A. (deposition date: 2019-10-07, release date: 2020-10-14, Last modification date: 2023-10-11)
Primary citationHuang, Q.,Cerione, R.A.
Crystal structure of human GAC in complex with inhibitor UPGL00012
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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