6UJM
Crystal structure of human GAC in complex with inhibitor UPGL00013
Summary for 6UJM
Entry DOI | 10.2210/pdb6ujm/pdb |
Descriptor | Glutaminase kidney isoform, mitochondrial, N-{5-[(3R)-3-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]amino}pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide (2 entities in total) |
Functional Keywords | inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 232832.86 |
Authors | Huang, Q.,Cerione, R.A. (deposition date: 2019-10-03, release date: 2020-10-07, Last modification date: 2023-10-11) |
Primary citation | Huang, Q.,Cerione, R.A. Crystal structure of human GAC in complex with inhibitor UPGL00013 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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