6UJC
Integrin alpha-v beta-8 in complex with the Fabs C6-RGD3 and 11D12v2
Summary for 6UJC
Entry DOI | 10.2210/pdb6ujc/pdb |
EMDB information | 20794 20795 20796 20797 20798 20799 20800 20801 20802 21125 |
Descriptor | Integrin alpha-V, Integrin beta-8, C6-RGD3 heavy chain Fab, ... (9 entities in total) |
Functional Keywords | glycoprotein, adhesion, signaling, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 244922.50 |
Authors | Campbell, M.G.,Cormier, A.,Cheng, Y.,Nishimura, S.L. (deposition date: 2019-10-02, release date: 2020-02-05, Last modification date: 2024-10-16) |
Primary citation | Campbell, M.G.,Cormier, A.,Ito, S.,Seed, R.I.,Bondesson, A.J.,Lou, J.,Marks, J.D.,Baron, J.L.,Cheng, Y.,Nishimura, S.L. Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta. Cell, 180:490-, 2020 Cited by PubMed: 31955848DOI: 10.1016/j.cell.2019.12.030 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.56 Å) |
Structure validation
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