6UII
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 5-[(3-aminopropyl)amino]pentane-1-thiol
Summary for 6UII
Entry DOI | 10.2210/pdb6uii/pdb |
Descriptor | Polyamine deacetylase HDAC10, 5-[(3-aminopropyl)amino]pentane-1-thiol, ZINC ION, ... (6 entities in total) |
Functional Keywords | histone deacetylase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Danio rerio (Zebrafish) |
Total number of polymer chains | 1 |
Total formula weight | 75630.45 |
Authors | Herbst-Gervasoni, C.J.,Christianson, D.W. (deposition date: 2019-10-01, release date: 2019-12-04, Last modification date: 2023-10-11) |
Primary citation | Herbst-Gervasoni, C.J.,Christianson, D.W. Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58:4957-4969, 2019 Cited by PubMed: 31746596DOI: 10.1021/acs.biochem.9b00906 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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