6UFP

Structure of proline utilization A with the FAD covalently modified by L-thiazolidine-2-carboxylate and three cysteines (Cys46, Cys470, Cys638) modified to S,S-(2-HYDROXYETHYL)THIOCYSTEINE

Summary for 6UFP

• Entry DOI: 10.2210/pdb6ufp/pdb
• Descriptor: Bifunctional protein PutA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, (2S)-1,3-thiazolidine-2-carboxylic acid, ... (9 entities in total)
• Functional Keywords: flavoenzyme, rossmann fold, proline catabolism, substrate channeling, bifunctional enzyme, oxidoreductase
• Biological source: Sinorhizobium meliloti (strain SM11); More
• Total number of polymer chains: 2
• Total formula weight: 268352.88

Authors

Campbell, A.C.,Tanner, J.J. (deposition date: 2019-09-24, release date: 2020-03-18, Last modification date: 2023-10-11)

• Primary citation: Campbell, A.C.,Becker, D.F.,Gates, K.S.,Tanner, J.J.; Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate.; Acs Chem.Biol., 15:936-944, 2020; PubMed: 32159324; DOI: 10.1021/acschembio.9b00935

Experimental method

X-RAY DIFFRACTION (1.737 Å)