6UEJ
Crystal structure of human zinc finger antiviral protein bound to RNA
Summary for 6UEJ
Entry DOI | 10.2210/pdb6uej/pdb |
Descriptor | Zinc finger CCCH-type antiviral protein 1, RNA (5'-R(P*UP*CP*G)-3'), ZINC ION, ... (5 entities in total) |
Functional Keywords | zinc finger antiviral protein, zap, rna binding domain, antiviral protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 27366.65 |
Authors | Meagher, J.L.,Smith, J.L. (deposition date: 2019-09-21, release date: 2019-11-13, Last modification date: 2023-10-11) |
Primary citation | Meagher, J.L.,Takata, M.,Goncalves-Carneiro, D.,Keane, S.C.,Rebendenne, A.,Ong, H.,Orr, V.K.,MacDonald, M.R.,Stuckey, J.A.,Bieniasz, P.D.,Smith, J.L. Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences. Proc.Natl.Acad.Sci.USA, 116:24303-24309, 2019 Cited by PubMed: 31719195DOI: 10.1073/pnas.1913232116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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