6UEJ

Crystal structure of human zinc finger antiviral protein bound to RNA

Summary for 6UEJ

• Entry DOI: 10.2210/pdb6uej/pdb
• Descriptor: Zinc finger CCCH-type antiviral protein 1, RNA (5'-R(P*UP*CP*G)-3'), ZINC ION, ... (5 entities in total)
• Functional Keywords: zinc finger antiviral protein, zap, rna binding domain, antiviral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27366.65

Authors

Meagher, J.L.,Smith, J.L. (deposition date: 2019-09-21, release date: 2019-11-13, Last modification date: 2023-10-11)

• Primary citation: Meagher, J.L.,Takata, M.,Goncalves-Carneiro, D.,Keane, S.C.,Rebendenne, A.,Ong, H.,Orr, V.K.,MacDonald, M.R.,Stuckey, J.A.,Bieniasz, P.D.,Smith, J.L.; Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences.; Proc.Natl.Acad.Sci.USA, 116:24303-24309, 2019; PubMed: 31719195; DOI: 10.1073/pnas.1913232116

Experimental method

X-RAY DIFFRACTION (2.21 Å)