6UC3

Spectroscopic and structural characterization of a genetically encoded direct sensor for protein-ligand interactions

6UC3 の概要

• エントリーDOI: 10.2210/pdb6uc3/pdb
• 分子名称: Streptavidin, BIOTIN (3 entities in total)
• 機能のキーワード: unnatural amino acid, non-canonical amino acid, fluorescence, biosensor, small molecule biosensor, ligand detection, biotin binding protein
• 由来する生物種: Streptomyces avidinii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29772.30

構造登録者

Mills, J.H.,Gleason, P.R.,Simmons, C.R.,Henderson, J.N.,Kartchner, B.K. (登録日: 2019-09-13, 公開日: 2020-09-16, 最終更新日: 2023-11-15)

• 主引用文献: Gleason, P.R.,Kolbaba-Kartchner, B.,Henderson, J.N.,Stahl, E.P.,Simmons, C.R.,Mills, J.H.; Structural Origins of Altered Spectroscopic Properties upon Ligand Binding in Proteins Containing a Fluorescent Noncanonical Amino Acid.; Biochemistry, 60:2577-2585, 2021; PubMed: 34415744; DOI: 10.1021/acs.biochem.1c00291

実験手法

X-RAY DIFFRACTION (1.84 Å)