6U9W

Cryo electron microscopy structure of the ATP-gated rat P2X7 ion channel in the ATP-bound, open state

Summary for 6U9W

Entry DOI	10.2210/pdb6u9w/pdb
EMDB information	20703
Descriptor	P2X purinoceptor 7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (8 entities in total)
Functional Keywords	ion channel apoptosis, membrane protein
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	3
Total formula weight	222198.46
Authors	Mansoor, S.E.,McCarthy, A.E. (deposition date: 2019-09-09, release date: 2019-10-23, Last modification date: 2020-07-29)
Primary citation	McCarthy, A.E.,Yoshioka, C.,Mansoor, S.E. Full-Length P2X7Structures Reveal How Palmitoylation Prevents Channel Desensitization. Cell, 179:659-670.e13, 2019 Cited by PubMed: 31587896 DOI: 10.1016/j.cell.2019.09.017 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation