6U5L

Structure of human ULK4 in complex with an inhibitor

6U5L の概要

• エントリーDOI: 10.2210/pdb6u5l/pdb
• 分子名称: Serine/threonine-protein kinase ULK4, N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: kinase, pseudokinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33191.07

構造登録者

Khamrui, S.,Lazarus, M.B. (登録日: 2019-08-28, 公開日: 2019-12-25, 最終更新日: 2023-10-11)

• 主引用文献: Khamrui, S.,Ung, P.M.U.,Secor, C.,Schlessinger, A.,Lazarus, M.B.; High-Resolution Structure and Inhibition of the Schizophrenia-Linked Pseudokinase ULK4.; J.Am.Chem.Soc., 142:33-37, 2020; PubMed: 31841327; DOI: 10.1021/jacs.9b10458

実験手法

X-RAY DIFFRACTION (1.75 Å)