6U4U

1.3 A structure of a pathogenic human Syt 1 C2B (I368T)

Summary for 6U4U

• Entry DOI: 10.2210/pdb6u4u/pdb
• Related: 1UOW
• Descriptor: Synaptotagmin-1, SULFATE ION (3 entities in total)
• Functional Keywords: c2 domain, c2b, greek key, exocytosis
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 18732.33

Authors

Dominguez, M.J.,Bradberry, M.M.,Chapman, E.R.,Sutton, R.B. (deposition date: 2019-08-26, release date: 2020-05-13, Last modification date: 2023-10-11)

• Primary citation: Bradberry, M.M.,Courtney, N.A.,Dominguez, M.J.,Lofquist, S.M.,Knox, A.T.,Sutton, R.B.,Chapman, E.R.; Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.; Neuron, 107:52-64.e7, 2020; PubMed: 32362337; DOI: 10.1016/j.neuron.2020.04.003

Experimental method

X-RAY DIFFRACTION (1.3 Å)