6U3J

Structure of the 2-oxoadipate dehydrogenase DHTKD1

Summary for 6U3J

• Entry DOI: 10.2210/pdb6u3j/pdb
• Descriptor: 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: lysine metabolism mitochondrial dehydrogenase, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 204599.84

Authors

Khamrui, S.,Lazarus, M.B. (deposition date: 2019-08-21, release date: 2020-07-22, Last modification date: 2023-10-11)

• Primary citation: Leandro, J.,Khamrui, S.,Wang, H.,Suebsuwong, C.,Nemeria, N.S.,Huynh, K.,Moustakim, M.,Secor, C.,Wang, M.,Dodatko, T.,Stauffer, B.,Wilson, C.G.,Yu, C.,Arkin, M.R.,Jordan, F.,Sanchez, R.,DeVita, R.J.,Lazarus, M.B.,Houten, S.M.; Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.; Acs Chem.Biol., 15:2041-2047, 2020; PubMed: 32633484; DOI: 10.1021/acschembio.0c00114

Experimental method

X-RAY DIFFRACTION (2.25 Å)