6U15
Human thymine DNA glycosylase N140A mutant bound to DNA with 2'-F-5-carboxyl-dC substrate analog
Summary for 6U15
Entry DOI | 10.2210/pdb6u15/pdb |
Descriptor | G/T mismatch-specific thymine DNA glycosylase, DNA (28-MER), ... (4 entities in total) |
Functional Keywords | protein-dna complex, hydrolase-dna complex, dna binding protein, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 43107.07 |
Authors | Pidugu, L.S.,Pozharski, E.,Drohat, A.C. (deposition date: 2019-08-15, release date: 2019-11-20, Last modification date: 2023-11-15) |
Primary citation | Pidugu, L.S.,Dai, Q.,Malik, S.S.,Pozharski, E.,Drohat, A.C. Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase. J.Am.Chem.Soc., 141:18851-18861, 2019 Cited by PubMed: 31693361DOI: 10.1021/jacs.9b10376 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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