6U15
Human thymine DNA glycosylase N140A mutant bound to DNA with 2'-F-5-carboxyl-dC substrate analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G/T mismatch-specific thymine DNA glycosylase | polymer | 227 | 25832.0 | 1 | UniProt (Q13569) Pfam (PF03167) | Homo sapiens (Human) | Thymine-DNA glycosylase,hTDG |
| 2 | B (C) | DNA (28-MER) | polymer | 28 | 8646.6 | 1 | synthetic construct | ||
| 3 | C (D) | DNA (28-MER) | polymer | 28 | 8628.5 | 1 | synthetic construct | ||
| 4 | D, E, F (A, C, D) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A: 82 - 308 (UniProt: Q13569)
| PDB | External Database | Details |
|---|---|---|
| Ala 140 | Asn 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 43107.1 | |
| All* | Total formula weight | 43107.1 |
