6TYH
Four-Disulfide Insulin Analog A22/B22
Summary for 6TYH
Entry DOI | 10.2210/pdb6tyh/pdb |
Descriptor | Insulin A chain, Insulin B chain, PHENOL, ... (8 entities in total) |
Functional Keywords | signalling, metabolism, hormone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 36361.31 |
Authors | Blakely, A.D.,Xiong, X. (deposition date: 2019-08-08, release date: 2019-11-13, Last modification date: 2020-03-11) |
Primary citation | Xiong, X.,Blakely, A.,Karra, P.,VandenBerg, M.A.,Ghabash, G.,Whitby, F.,Zhang, Y.W.,Webber, M.J.,Holland, W.L.,Hill, C.P.,Chou, D.H. Novel four-disulfide insulin analog with high aggregation stability and potency. Chem Sci, 11:195-200, 2020 Cited by PubMed: 32110371DOI: 10.1039/c9sc04555d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.60001899481 Å) |
Structure validation
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