6TYG
Crystal structure of MTB sigma L transcription initiation complex with 9 nt long RNA primer
Summary for 6TYG
Entry DOI | 10.2210/pdb6tyg/pdb |
Descriptor | RNA polymerase sigma factor, DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), ... (8 entities in total) |
Functional Keywords | transcription, tuberculosis, initiation, sigma finger displacement |
Biological source | Mycobacterium tuberculosis More |
Total number of polymer chains | 9 |
Total formula weight | 401271.80 |
Authors | Molodtsov, V.,Ebright, R.H. (deposition date: 2019-08-08, release date: 2020-03-11, Last modification date: 2023-10-11) |
Primary citation | Li, L.,Molodtsov, V.,Lin, W.,Ebright, R.H.,Zhang, Y. RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117:5801-5809, 2020 Cited by PubMed: 32127479DOI: 10.1073/pnas.1920747117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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