6TWT

Crystal structure of N-terminally truncated NDM-1 metallo-beta-lactamase

Summary for 6TWT

• Entry DOI: 10.2210/pdb6twt/pdb
• Related: 3ZR9 6OGO 6OL8
• Descriptor: Metallo beta lactamase NDM-1, ZINC ION, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: metallo-beta-lactamase, ndm-1, antibiotic resistance, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 52219.89

Authors

Imiolczyk, B.,Czyrko-Horczak, J.,Brzezinski, K.,Jaskolski, M. (deposition date: 2020-01-13, release date: 2020-05-13, Last modification date: 2024-01-24)

• Primary citation: Raczynska, J.E.,Imiolczyk, B.,Komorowska, M.,Sliwiak, J.,Czyrko-Horczak, J.,Brzezinski, K.,Jaskolski, M.; Flexible loops of New Delhi metallo-beta-lactamase modulate its activity towards different substrates.; Int.J.Biol.Macromol., 158:104-115, 2020; PubMed: 32353499; DOI: 10.1016/j.ijbiomac.2020.04.219

Experimental method

X-RAY DIFFRACTION (0.95 Å)