6TUZ

Theophylline-Notum complex

Summary for 6TUZ

Entry DOI	10.2210/pdb6tuz/pdb
Descriptor	Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
Functional Keywords	wnt notum inhibitor complex, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	46002.73
Authors	Zhao, Y.,Jones, E.Y. (deposition date: 2020-01-08, release date: 2020-10-28, Last modification date: 2024-01-24)
Primary citation	Zhao, Y.,Ren, J.,Hillier, J.,Lu, W.,Jones, E.Y. Caffeine inhibits Notum activity by binding at the catalytic pocket. Commun Biol, 3:555-555, 2020 Cited by PubMed: 33033363 DOI: 10.1038/s42003-020-01286-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation