6TRO
Crystal structure of the T-cell receptor GVY01 bound to HLA A2*01-GVYDGREHTV
Summary for 6TRO
Entry DOI | 10.2210/pdb6tro/pdb |
Related | 6TRN |
Descriptor | MHC class I antigen, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239), ... (6 entities in total) |
Functional Keywords | human leukocyte antigen, mage-a4, t-cell receptor, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 96383.17 |
Authors | Coles, C.H.,McMurran, C.,Lloyd, A.,Hibbert, L.,Lupardus, P.J.,Cole, D.K.,Harper, S. (deposition date: 2019-12-19, release date: 2020-06-24, Last modification date: 2024-01-24) |
Primary citation | Coles, C.H.,McMurran, C.,Lloyd, A.,Hock, M.,Hibbert, L.,Raman, M.C.C.,Hayes, C.,Lupardus, P.,Cole, D.K.,Harper, S. T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4. J.Biol.Chem., 295:11486-11494, 2020 Cited by PubMed: 32532817DOI: 10.1074/jbc.RA120.014016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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